Journal: Journal of Health Economics and Outcomes Research

Article Title: Are Trends in Economic Modeling of Pediatric Diabetes Mellitus up to Date with the Clinical Practice Guidelines and the Latest Scientific Findings?

doi: 10.36469/001c.127920

Figure Lengend Snippet: Description of the Economic Models Included in the Literature Review

Article Snippet: , , Deterministic Markov model d , Data TreeAge® , This Markov model includes 17 health states derived from the 7 more frequent complications in diabetes, including their pairwise combinations (representing the presence of 2 complications at the same time in the same patient). The diabetic complications considered are amputation (toe, foot, or leg), blindness (macular edema or diabetic retinopathy), CVD (nonlethal MI, silent MI, revascularization, angina and nonlethal ictus), ESRD, diabetic neuropathy, and death. The model was designed to study the transplantation of islet cells, which can cause PTLD in a proportion of patients, thus, this was accounted for in the cohort who received that intervention, leading to 33 health states. The effectiveness of the surgery affects the results of the economic evaluation. This effectiveness is measured by terms of the graft complete and partial function, or the graft failure based on the insulin requirements and C-peptide–detectable presence..

Techniques: Software, Infection, Derivative Assay, Biomarker Discovery, Control, Transplantation Assay